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Citalopram overdose





Celexa (Citalopram Hydrobromide) Drug Information Overdosage

6/18/2014
01:43 | Author: Kate Thompson

Citalopram overdose
Celexa (Citalopram Hydrobromide) Drug Information Overdosage

Symptoms most often accompanying citalopram overdose, alone or in combination with other drugs and/or alcohol, included dizziness, sweating, nausea.

The use of Celexa within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated (see WARNINGS and DOSAGE AND ADMINISTRATION ). The use of MAOIs intended to treat psychiatric disorders with Celexa or within 14 days of stopping treatment with Celexa is contraindicated because of an increased risk of serotonin syndrome.

Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Citalopram overdose - Life in the Fast Lane

4/17/2014
01:46 | Author: Evan Martin

Citalopram overdose
Citalopram overdose - Life in the Fast Lane

Your next patient is a 26 year-old female who claims to have ingested 40 x citalopram hydrobromide tablets (40mg each) about 3 hours ago. She appears.

Emergency medicine and critical care medical education blog by Chris Nickson.

Alternative corrections that have been proposed are:

Chan et al’s analysis suggests that their nomogram outperforms Bazett’s correction for predicting pro-arrhythmic risk, with sensitivities and specificities >96.9%. Chan et al (2007) have evaluated an approach to the assessment of pro-arrhythmic risk in QT prolongation using a nomogram, which does not require the use of correction formulas or numerous previous ECGs required for individual HR correction.

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Citalopram overdose MHRA

12/26/2014
07:31 | Author: Cole Thomas

Citalopram overdose
Citalopram overdose MHRA

Fatal dose not known. Patients have survived ingestion of up to 2 g citalopram. The effects will be potentiated by alcohol taken at the same time.

This includes alteration of mental status, neuromuscular hyperactivity and autonomic instability. Rhabdomyolysis is rare. Rarely, features of the "serotonin syndrome" may occur in severe poisoning. There may be hyperpyrexia and elevation of serum creatine kinase.

In Overdose sections of SPCs.

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Home How we regulate Medicines Licensing of medicines Information for licence holders Guidance Overdose sections of SPCs 'Generic' overdose sections Citalopram.

Patients have survived ingestion of up to 2 g citalopram. The effects will be potentiated by alcohol taken at the same time. Fatal dose not known. Potential interaction with tricyclic antidepressants and MAOIs.

Prolonged bradycardia with severe hypotension and syncope has also been reported. Cardiac features that have been observed include nodal rhythm, prolonged QT intervals and wide QRS complexes. Symptoms Nausea, vomiting, sweating, tachycardia, drowsiness, coma, dystonia, convulsions, hyperventilation and hyperpyrexia have been reported.

Control convulsions with intravenous diazepam if they are frequent or prolonged. An ECG should be taken.

Observe for a minimum of 4 hours due to long half life of citalopram. Management Management should be symptomatic and supportive and include the maintenance of a clear airway and monitoring of cardiac and vital signs until stable. Consider oral activated charcoal in adults and children who have ingested more than 5 mg/kg body weight within 1 hour.

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Citalopram 20mg Tablets - Summary of Product Characteristics (SPC)

10/25/2014
05:12 | Author: Evan Martin

Citalopram overdose
Citalopram 20mg Tablets - Summary of Product Characteristics (SPC)

Citalopram 20mg Tablets: 1 film-coated tablet contains 24.99 mg citalopram.. Fatal cases of citalopram overdose have been reported with.

Find medicines with the same active ingredients.

The use of citalopram in patients with severe renal impairment (creatinine clearance less than 20ml/min.) is not recommended as no information is available on use in these patients. Hyponatraemia. (see section 4.2) In cases of impaired hepatic function dose reduction is recommended (see section 4.2) and liver function has to be closely monitored.

Last Updated on eMC 21-Jul-2014 View changes| Actavis UK Ltd Contact details.

This mydriatic effect has the potential to narrow the eye angle resulting in increased intraocular pressure and angle-closure glaucoma, especially in patients pre-disposed.

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Case report of a fatal intoxication by citalopram

8/24/2014
03:25 | Author: Kate Thompson

Citalopram overdose
Case report of a fatal intoxication by citalopram

Citalopram is an antidepressant drug within the group of the selective serotonin and most cases of overdose, even with high doses of citalopram ingested, are.

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We report the exact concentrations of the citalopram in the organs, and wethink that this can be useful in the cases where the blood samples were not available (ie, carbonized or decomposed body). Citalopram is an antidepressant drug within the group of the selective serotonin reuptake inhibitors (SSRI). The autopsy findings were unremarkable. Citalopram separation was performed by solid/liquid method, using Bond-Elute columns. She had been prescribed citalopram by her family doctor 3 weeks before her death for a depressive syndrome. Nasal swabs, blood from femoral vein, urine, bile and tissue samples were collected for toxicologic investigation. Our data confirm that if no other drug is involved, fatal complications occur only after ingestion of very high doses. Police found in her house 3 empty blister packages of 28 citalopram tablets (20 mg) and 2 bottles of citalopram oral solution (4%, 15 mL each). The extracts were analyzed by GLC and GC/MS methods. However, there is no predefined "toxic dose," and the conditions under which the overdose occurs can be very important. The toxicologic analysis showed high levels of citalopram in all the examined fluids and tissue samples (blood concentration: 11.60 mg/L). We report the case of a young woman found dead at home. It is widely prescribed both in Europe and in United States, and it has always been considered a "safe" drug as pure intoxication with lethal outcome is rare, and most cases of overdose, even with high doses of citalopram ingested, are reported to have an uneventful course. No other drugs and alcohol were detected.

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