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Sodium phosphate tablets and acute phosphate nephropathy





Science Background Paper Acute Phosphate Nephropathy

7/9/2014
12:35 | Author: Kate Thompson

Sodium phosphate tablets and acute phosphate nephropathy
Science Background Paper Acute Phosphate Nephropathy

Documented cases of acute phosphate nephropathy include 21 patients (40 tablets) provide nearly identical amounts of sodium phosphate:.

Use OSP with caution in patients taking diuretics, ACE inhibitors, ARBs, and NSAIDs.

The hyperphosphatemia increases phosphate levels in the renal tubules. An abnormally high product in renal tubular fluid causes precipitation of calcium-phosphate crystals in the kidney and the pattern of renal injury described above. Bowel cleansing with OSP causes dehydration, decreased intravascular volume, and hyperphosphatemia (due to a large oral phosphate load). Decreased intravascular volume stimulates reabsorption of water from the renal tubules further increasing the phosphate concentration in renal tubular fluid.

Use hospitalization and intravenous hydration during bowel cleansing to support frail patients who may be unable to drink an appropriate volume of fluid or may be without assistance at home.

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Sodium phosphate tablets and acute phosphate nephropathy

5/8/2014
02:30 | Author: Caitlin White

Sodium phosphate tablets and acute phosphate nephropathy
Sodium phosphate tablets and acute phosphate nephropathy

Am J Gastroenterol. 2009 Aug;104(8):1903-6. doi: 10.1038/ajg.2009.342. Sodium phosphate tablets and acute phosphate nephropathy. Mackey AC, Green L.

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Acute Phosphate Nephropathy

3/7/2014
04:45 | Author: Kate Thompson

Sodium phosphate tablets and acute phosphate nephropathy
Acute Phosphate Nephropathy

Acute phosphate nephropathy (APN) is an underrecognized cause of both acute and APN has been reported to occur after exposure to sodium-phosphate (NaP) The protocol entails taking 3 tablets with 8 ounces of clear liquid every 15.

They remain the most commonly used preparation for endoscopic bowel procedures. 5. There have been variations on this preparation in an attempt to improve the taste and thus improve patient compliance with these protocols. 5 The main complaint from patients in using this preparation has been its taste and the large volume of the solution used in the preparation for their procedures. Currently, the method most commonly used is a balanced-electrolyte solution, such as the polyethylene glycol (PEG) in Colyte.

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Acute phosphate nephropathy - UpToDate

11/16/2014
04:20 | Author: Caitlin White

Sodium phosphate tablets and acute phosphate nephropathy
Acute phosphate nephropathy - UpToDate

Acute phosphate nephropathy is a form of kidney injury that occurs following the use of bowel purgatives that contain oral sodium phosphate.

UpToDate synthesizes the most recent medical information into evidence-based practical recommendations clinicians trust to make the right point-of-care decisions.

Although long used as a laxative, OSP began to be used as a purgative for colonoscopy in 1990. It is frequently given in favor of standard polyethylene glycol (PEG)-based lavage solutions because of the smaller required volume, which results in better patient compliance and improved colonic cleansing.

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This clinicopathologic entity has been referred to as acute phosphate nephropathy.

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Monobasic Sodium Phosphate and Dibasic Sodium

9/15/2014
02:35 | Author: Kate Thompson

Sodium phosphate tablets and acute phosphate nephropathy
Monobasic Sodium Phosphate and Dibasic Sodium

There have been rare, but serious reports of acute phosphate nephropathy in patients. In a single pharmacokinetic study of sodium phosphate tablets, which.

Because published data suggest that sodium phosphate absorption may be enhanced in patients experiencing an acute exacerbation of chronic inflammatory bowel disease, Monobasic Sodium Phosphate and Dibasic Sodium Phosphate Tablets should be used with caution in such patients.

Monobasic sodium phosphate, USP.

In controlled colon preparation trials of Monobasic Sodium Phosphate and Dibasic Sodium Phosphate Tablets, 228 (24%) of 931 patients were 65 years of age or older.

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