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Long term effects of zopiclone





A sleep laboratory evaluation of the long-term efficacy of zopiclone

9/20/2014
04:13 | Author: Kate Thompson

Long term effects of zopiclone
A sleep laboratory evaluation of the long-term efficacy of zopiclone

A sleep laboratory evaluation of the long-term efficacy of zopiclone. Fleming JA The commonest side effect was a bitter or metallic taste. No significant.

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To qualify for the study, sleep efficiency, determined by a sleep study on two, consecutive, placebo-controlled nights, had to be less than 75%. Zopiclone (7.5 mg) increased sleep efficiency by decreasing sleep latency, wakefulness after sleep onset and increasing total sleep time. Sleep architecture was minimally affected by zopiclone treatment; no significant changes in delta or REM sleep were observed. These findings indicate that zopiclone is a safe and effective hypnotic medication which maintains its effectiveness with protracted use. Patients evaluated their sleep by questionnaire and had sleep studies completed throughout active treatment. Six patients between the ages of 25 and 59, with chronic, primary insomnia received the new, non-benzodiazepine, hypnotic zopiclone continuously for 17 weeks after a drug free interval of 12 nights. No significant changes in biological functioning were noted throughout the study period. The commonest side effect was a bitter or metallic taste.

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Benefits and risks of long-term sleep meds Phoenix Rising ME

7/19/2014
02:14 | Author: Evan Martin

Long term effects of zopiclone
Benefits and risks of long-term sleep meds Phoenix Rising ME

After years of insomnia (problems getting to sleep rather than would like to know if anyone is on long-term sleep meds, particularly Zopiclone.

Discussion in ' General Treatment ' started by darkrobot, Jun 28, 2010.

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A Qualitative Investigation of Long-Term Zopiclone Use and Sleep

5/18/2014
12:21 | Author: Cole Thomas

Long term effects of zopiclone
A Qualitative Investigation of Long-Term Zopiclone Use and Sleep

Objective: To examine the effects of the extended use of zopiclone among a to examine the consequences of long-term zopiclone therapy for PTSD-related.

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Effect of withdrawal from long-term use of temazepam, zopiclone or

3/17/2014
02:08 | Author: Evan Martin

Long term effects of zopiclone
Effect of withdrawal from long-term use of temazepam, zopiclone or

Purpose. The aim of this study was to assess the effect of withdrawal from the long-term use of temazepam, zopiclone or zolpidem as hypnotics.

Ninety-two adults (age ≥55 years) with primary insomnia and who were long-term daily users of BZD volunteered to participate in a 1-month medically supported withdrawal attempt from BZD use, with a subsequent 5-month follow-up. Attention and psychomotor performance were measured using the CogniSpeed at baseline and at 1, 2 and 6 months. Withdrawal was based on plasma BZD measurements at baseline, at 1 month and during subsequent regular clinical appointments. The cognition data of the withdrawal group were also compared with a cohort of BZD non-users.

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Effect of withdrawal from long-term use of temazepam, zopiclone or

1/16/2014
04:25 | Author: Kate Thompson

Long term effects of zopiclone
Effect of withdrawal from long-term use of temazepam, zopiclone or

ABSTRACT The aim of this study was to assess the effect of withdrawal from the long-term use of temazepam, zopiclone or zolpidem as hypnotics drugs (here.

Reaction times were determined in the Simple Reaction Time (SRT), Two-Choice Reaction Time (2-CRT) and Vigilance tests, and errors were measured by the 2-CRT and Vigilance tests. Ninety-two adults (age ≥55 years) with primary insomnia and who were long-term daily users of BZD volunteered to participate in a 1-month medically supported withdrawal attempt from BZD use, with a subsequent 5-month follow-up. Compared to the reaction times of the BZD-free cohort, those of BZD users were slower at baseline. The cognition data of the withdrawal group were also compared with a cohort of BZD non-users. Attention and psychomotor performance were measured using the CogniSpeed at baseline and at 1, 2 and 6 months. Eighty-nine (97 %) participants (59 women, 30 men) were followed-up for a maximum of 6 months. Long-term use of BDZ as hypnotic drugs by older adults is related to prolonged impairment of attentional and psychomotor cognitive functioning that persists for at least 6 months after withdrawal. During the follow-up period, changes in reaction times and errors did not differ between short-term withdrawers (no residual BZD at 1 month; N = 69), non-withdrawers (residual BZD at 1 month; N = 20) or long-term withdrawers (N = 34). ABSTRACT The aim of this study was to assess the effect of withdrawal from the long-term use of temazepam, zopiclone or zolpidem as hypnotics drugs (here referred to as BZD) on cognitive performance. Withdrawal was based on plasma BZD measurements at baseline, at 1 month and during subsequent regular clinical appointments. The reaction times of BZD withdrawers based on the results of the SRT or 2-CRT tests during follow-up did not reach those of the BZD-free cohort, but there was no difference between these groups in the Vigilance test.

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