A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Death by zopiclone





Comparison of the fatal toxicity index of zopiclone with

01/27/2015
11:39 | Author: Christina Harris

Death by zopiclone
Comparison of the fatal toxicity index of zopiclone with

Hypnosedatives were the sole agents in only one death and were the primary agents in eight deaths. Zopiclone was the sixth most commonly involved agent in.

National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA. National Center for Biotechnology Information, U.S.

Zopiclone is a hypnosedative structurally unrelated to the benzodiazepines but operating at the same receptor complex. Although zopiclone has been used in clinical practice for many years, relatively little is known of its relative toxicity in comparison with other hypnosedatives.

Warning: The NCBI web site requires JavaScript to function. more.

Deaths, where hypnosedatives were implicated, in New Zealand (NZ) in 2001 were identified from a chemical injury database. Rates of death per prescription and DDD, and relative rates between individual hypnosedatives and benzodiazepines, and their respective 95% CI were calculated. Prescription and aggregate defined daily dose (DDD) data forNZ in 2001 were obtained from a national prescribing database.

Hypnosedatives were the sole agents in only one death and were the primary agents in eight deaths. The relative rate of death per prescription (95% CI) and DDD (95% CI) of zopiclone compared with benzodiazepines were 1.04 (0.49-2.05) and 0.59 (0.28-1.16), respectively. The relative rates of death per DDD (95% CI) for alprazolam and chlormethiazole compared with the other sedatives/anxiolytics were 6.2 (1.6-17.0) and 20.9 (2.5-79.8) respectively. Zopiclone was the sixth most commonly involved agent in poisoning deaths in NZ in 2001. Of the 200 poisoning deaths in NZ for 2001, 39 involved hypnosedatives, and zopiclone was involved in 12.

Generate a file for use with external citation management software.

Hypnosedatives are contributory factors rather than primary substances in poisoning deaths. The fatal toxicity for zopiclone was not significantly different from that for benzodiazepines as a group when adjusted for usage, whereas alprazolam and chlormethiazole had greater toxicity.

Comments (0)



Heard of 39Zopiclone39 and 39Olanzapine39? More and more people

01/27/2015
09:18 | Author: Evan Martin

Death by zopiclone
Heard of 39Zopiclone39 and 39Olanzapine39? More and more people

Again, it was the main drug behind 22 deaths that year — an increase of 12 Drugs like Zopiclone and Olanzapine are commonly taken in.

Drugs like Zopiclone and Olanzapine are commonly taken in combination with other substances by drug users, with the aim of achieving a specific effect.

Alternatively, you can us at:

So what’s behind the increase?

Notify me of followup comments via.

However, there haven’t been any large-scale seizures recently. Large quantities, if found, can be dealt with under criminal justice legislation.

To embed this post, copy the code below on your site.

“They’re both prescribed drugs,” Dr Bobby Smyth of the Drug Treatment Centre Board says.

Heard of ‘Zopiclone’ and ‘Olanzapine’? … More and more people are dying after taking them Comments.

Further down the list, the two prescription drugs mentioned above were the main substances recorded in over 70 deaths between 2011 and 2012.

is a full participating member of the Press Council of Ireland and supports the Office of the Press Ombudsman.

Comments (2)Read more