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Zopiclone pregnancy





Pregnancy outcome following first-trimester exposure to zopiclone a

01/20/2015
11:30 | Author: Caitlin White

Zopiclone zolpidem
Pregnancy outcome following first-trimester exposure to zopiclone a

Am J Perinatol. 1999;16(4):157-60. Pregnancy outcome following first-trimester exposure to zopiclone: a prospective controlled cohort study. Diav-Citrin O(1).

Pregnancy outcome was compared with that of a matched control group of women, who were counseled for nonteratogenic exposure. The Motherisk Program, the Toronto Teratogen Information Service, prospectively collected and followed up 40 women exposed to zopiclone during pregnancy.

The purpose of this study was to compare pregnancy outcome following first-trimester exposure to zopiclone with that of a matched control group of women, who were counseled for nonteratogenic exposure. To date, no published data exist regarding human pregnancy experience with zopiclone. Zopiclone, a cyclopyrrolone derivative, is a short-acting hypnotic.

1 of 37 for nonteratogenic controls; p = 1). There was no increase in the rate of major malformations (0 of 31 for zopiclone vs.

National Center for Biotechnology Information, U.S. National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA.

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Larger studies are needed to establish its safety during pregnancy. Our study, which is the first cohort on zopiclone use during embryogenesis, albeit small, suggests that zopiclone does not appear to be a major human teratogen.

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Psychotropic drug use during pregnancy benzodiazepines

01/20/2015
09:00 | Author: Caitlin White

Zopiclone deep sleep
Psychotropic drug use during pregnancy benzodiazepines

In addition to the adverse effects associated with use of benzodiazepines, zolpidem and zopiclone during pregnancy, there is also the risk of dependence.

Psychotropic drug use during pregnancy: nonprescribed psychoactive drugs.

A high-resolution ultrasound examination at 18 to 20 weeks should be considered for such women, and refer to a specialist centre if necessary. Pooled data from prospective cohort studies have shown no increase in malformations. The issue of whether first trimester exposure to benzodiazepines is associated with increased risk of cleft lip and/or palate is controversial. However, poorer quality, case-control studies have shown an association between exposure to benzodiazepines and major malformations or oral cleft alone.

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