Hypersensitivity side effects including rare cases of angioedema involving the tongue, glottis or larynx have been reported in patients after taking the first or subsequent doses of sedative-hypnotics, including zolpidem (the active ingredient contained in Ambien) Some patients have had additional symptoms such as dyspnea, throat closing, or nausea and vomiting that suggest anaphylaxis.
Possible side effects of Ambien:
Gastrointestinal. Patients who develop angioedema after treatment with zolpidem should not be rechallenged with the drug. Some patients have required medical therapy in the emergency department. If angioedema involves the throat, glottis or larynx, airway obstruction may occur and be fatal.
Stop taking zolpidem (the active ingredient contained in Ambien) and Get emergency medical help if you have any of these signs of an allergic reaction while taking zolpidem: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Zolpidem may cause a severe allergic reaction.
Musculoskeletal side effects including arthralgia and myalgia have been reported. Important safety information:.
Musculoskeletal. Immunologic side effects including infection have been reported infrequently.
Less serious side effects of zolpidem may include:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:.
Seek medical attention right away if any of these SEVERE side effects occur:
Withdrawal symptoms may include agitation, restlessness, anxiety, depression, insomnia, tremor, nausea, abdominal discomfort, and sweating. Other side effects including tolerance to the pharmacologic effects of zolpidem (the active ingredient contained in Ambien) have been reported rarely. Withdrawal symptoms after either abrupt cessation or fast tapering may occur. A case of sleep driving has also been reported. Other side effects associated with the oral spray have included dry mouth. Psychiatric.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the hands, legs, mouth, face, lips, eyes, throat, or tongue; throat closing; unusual hoarseness); abnormal thinking; behavior changes; chest pain; confusion; decreased coordination; difficulty swallowing or breathing; fainting; fast or irregular heartbeat; hallucinations; memory problems (eg, memory loss); mental or mood changes (eg, aggression, agitation, anxiety); new or worsening depression; severe dizziness; shortness of breath; suicidal thoughts or actions; vision changes.
Seizures may rarely occur. In more severe cases, you may have stomach and muscle cramps, vomiting, sweating, and shakiness. This may include unpleasant feelings. If you take Ambien for more than 1 to 2 weeks, do not stop taking it without talking to your doctor. If you stop taking Ambien suddenly, you may have WITHDRAWAL symptoms.
Diarrhea; dizziness; drowsiness (including daytime drowsiness); "drugged" feeling; dry mouth; headache; nausea; nose or throat irritation; sluggishness; stomach upset; weakness.
This is not a complete list of side effects and others may occur. For Healthcare Professionals Nervous system. Call your doctor for medical advice about side effects.
Stop using zolpidem and call your doctor at once if you have a serious side effects:
When sleep medicines are used every night for more than a few weeks, they may lose their effectiveness to help you sleep. If your sleep problems continue, contact your doctor. Sleep medicines should usually be used only for short periods of time, such as a few days and generally no longer than 1 or 2 weeks. This is known as TOLERANCE.
Read more at http://www.drugs.com/cdi/ambien.html#QhoI96FIkK87AZ95.99.
Immunologic. Hepatic side effects include one case of hepatotoxicity associated with zolpidem (the active ingredient contained in Ambien) given alone at therapeutic doses.
Respiratory. Psychiatric side effects including cases of psychotic reactions have been reported in association with zolpidem (the active ingredient contained in Ambien) therapy.
Nervous system side effects most frequently have included visual disturbances, ataxia, and dizziness. Hypersensitivity. Headache, drugged feeling, confusion, anterograde amnesia, excessive sedation, lightheadedness, delirium, nightmares, hallucinations, nervousness, and agitation have also been reported.
If you have questions about side effects, contact your health care provider. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA. This is not a complete list of all side effects that may occur. Call your doctor for medical advice about side effects.
Cardiovascular side effects including palpitations have been reported in patients taking zolpidem (the active ingredient contained in Ambien) Genitourinary.
When used for longer than a few weeks or at high doses, some people develop a need to continue taking Ambien. This is known as DEPENDENCE or addiction. Be sure to l your doctor if you have been dependent on alcohol, prescription medicines, or street drugs in the past.
Other. Gastrointestinal side effects have included nausea, vomiting, dyspepsia, anorexia, and diarrhea. In clinical studies on the sublingual tablet, one patient developed transient sublingual erythema and another patient developed transient paresthesia of the tongue.
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Zolpidem-induced respiratory depression may be responsive to flumazenil. Zolpidem-induced respiratory depression is generally not clinically significant at the usual hypnotic doses even in patients with impaired respiratory function. One study has suggested that zolpidem (the active ingredient contained in Ambien) doses of 20 mg (twice the usual dose) may cause apneic episodes in patients with obstructive sleep apnea.
Contact (the American Association of Poison Control Centers), your local poison control center, or emergency room immediay. Symptoms may include severe drowsiness or coma.
Genitourinary side effects including urinary incontinence and urinary tract infection have been reported. Hepatic.
Report any new or worsening symptoms to your doctor, such as: depression, anxiety, aggression, agitation, confusion, unusual thoughts, hallucinations, memory problems, changes in personality, risk-taking behavior, decreased inhibitions, no fear of danger, or thoughts of suicide or hurting yourself.
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Cardiovascular. Upper respiratory infection and rhinitis have also been reported. Respiratory side effects have included respiratory depression which may occur at high doses.
Cases of falls have been reported in elderly patients. Chronic use in high doses and subsequent withdrawal may induce grand mal seizures.
If OVERDOSE is suspected:
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