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Renal phosphate transport





Disorders of Renal Tubular Phosphate Transport

11/19/2014
02:21 | Author: Cole Thomas

Renal phosphate transport
Disorders of Renal Tubular Phosphate Transport

The kidney plays a major role in the maintenance of inorganic phosphate (Pi) homeostasis and, as such, ensures that an adequate supply of.

Hyp mice harbor a large 3′ deletion in the Phex gene ( 62, 63 ), whereas Gy mice have a deletion in the 5′ region that includes the upstream gene, spermine synthase ( 63 ). Mutations in the Phex gene have also been identified in the Hyp and Gy models of the human disease. Gy is thus a contiguous gene deletion syndrome, which may explain why these mutants exhibit phenotypic features that are not apparent in Hyp mice (see reference 51 ).

Influx of P i from the tubular lumen into the epithelial cell involves brush border membrane-associated Na/P i cotransporter(s) which are rate-limiting and targets for physiologic/pathophysiologic regulation.

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Genetic Disorders of Renal Phosphate Transport NEJM

11/18/2014
12:18 | Author: Caitlin White

Renal phosphate transport
Genetic Disorders of Renal Phosphate Transport NEJM

During the past decade, our knowledge of the mechanisms of renal phosphate transport has greatly improved: several phosphate transporters.

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The Regulation of Renal Phosphate Transport - ScienceDirect

9/17/2014
02:23 | Author: Christina Harris

Pi transport
The Regulation of Renal Phosphate Transport - ScienceDirect

Renal phosphate transport is mediated by the abundance and activity of the sodium-dependent phosphate transporters, Npt2a, Npt2c, and.

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Renal phosphate handling Physiology Prasad N, Bhadauria D

7/16/2014
04:56 | Author: Evan Martin

Pi transport
Renal phosphate handling Physiology Prasad N, Bhadauria D

Renal phosphate handling is regulated by three organs parathyroid, suggesting that there must be active transport of phosphate into cells.

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SGK3 a novel regulator of renal phosphate transportquest - Nature

5/15/2014
06:55 | Author: Kate Thompson

Pi transport
SGK3 a novel regulator of renal phosphate transportquest - Nature

Phosphate transport in the small intestine and renal tubules is mediated mainly by three type II sodium–phosphate cotransporters: NaPi-2a (SLC34A1), NaPi-2b.

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